Cognivin®’s Proprietary Herbal Blend includes herbals long revered in alternative medicinal therapies, along with a class of herbs called adaptogens. Adaptogens are valued for their unique ability to help the body maintain a state of balance—if stressed, they will calm without producing drowsiness, if fatigued they supply a boost of energy.  

Rhodiola rosea extract, a classic adaptogen, provides sustained energy. In one clinical study subject who received Rhodiola rosea instead of placebo showed significant improvement in measures of mental fatigue as tested through associative thinking, short-term memory, calculation, concentration, and speed of audio-visual perception after all-night work shifts. In another study significant improvement in physical fitness, mental fatigue, neuro-motoric tests, and well-being was reported in the treatment group. 

Ashwagandha (Withania somnifera) extract, sometimes called, “Indian Ginseng,” is valued for its adpatogenic effects of elevating mood, reducing stress and anxiety. It also has been found to provide sustained energy.  Subjects administered Withania somnifera prior to stressful situations had significantly fewer negative physical and emotional reactions. They were thus able to cope with stress better than those administered placebo.  

Asparagus racemosus has been used in alternative therapies as a treatment for nervousness. It reduces stress and anxiety. It helps elevate mood. Studies showed its anti-stress effects against a variety of stressors. 

Bacopa monnieri extract creates alert state of mind with heightened focus and concentration and increases memory retention. A double-blind, placebo-controlled study demonstrates that daily supplementation with Bacopa monniera significantly improves speed of visual information processing, learning rate, and memory consolidation as measured by neuropsychological tests. In another double-blind, placebo-controlled trial studying the effects of Bacopa monneri on memory in adults aged 40-65 years it was demonstrated that daily supplementation significantly increased subjects’ ability to retain new information.  

Emblica officinalis was shown to exert significant anti-stress effects against a variety of stressors. Not only does Emblica officinalis reduce stress, also reduces anxiety and elevates mood. 

Hops flower extract (Humulus lupulus) elevates mood. It has long recognized for its sedative effects and is used to relieve tension and nervousness. It also reduces anxiety and stress.  

Passion flower extract (Passiflora incarnata) was demonstrated to be an effective remedy for anxiety.  It reduces stress. It is also known to elevate mood. In a randomized, double-blind trial passionflower extract was shown to be effective in treating generalized anxiety disorder with fewer side effects than a drug commonly used to treat anxiety.

Terminalia arjuna reduces stress and anxiety. Terminalia arjuna is known for its strong medicinal properties in patients suffering from a variety of disorders.  Notably, Terminalia arjuna helps reduce feelings of stress and anxiety as it has been proven to potently reverse stress-associated physiological events like hypertension and cardiovascular disorders.

Tinospora cordifolia is reported to possess adpatogenic properties. It elevates mood and reduces anxiety and stress. It was shown to exert significant anti-stress effects against a variety of stressors.  

Ginkgo biloba creates an alert state of mind with heightened focus and concentration. In double-blind, placebo-controlled studies, Ginkgo biloba supplementation demonstrated significant improvements in “speed of attention” and faster short-term memory processing compared to the placebo group. Ginkgo improves memory. In one study, Ginkgo use significantly improved free recall and recognition of auditory, verbal, and visual material. It also improves cognitive function and counteracts cognitive decline. Study after study reveals use of Ginkgo biloba’ improved s effectiveness in the treatment of dementia, cerebral insufficiency. In patients suffering from dementia Ginkgo supplementation demonstrated significant improvements in psychopathological symptoms, memory and attention, and behavioral assessments.

Choline Bitartrate improves memory retention. In studies its use caused significant improvement in explicit memory and the ability to master a serial-learning word test. In a placebo controlled study elderly subjects with memory deficits, but without dementia, showed improved memory in free recall tasks.

Vinpocetine provides multiple cognitive benefits. It has been shown to significantly improve memory retention in double-blind, placebo-controlled trials with patients with chronic cerebral dysfunction or dementia.  Vinpocetine creates an alert state of mind with heightened focus and concentration. Subjects given this ingredient exhibited faster short term memory processing than was found in the placebo group.  It also improves cognitive function / counteracts cognitive decline. Following administration of vinpocetine, patients suffering from dementia demonstrated statistically significant improvements in “Global Improvement” and cognitive performance and reductions in severity of illness. Two clinical trials show that vinpocetine enhances brain metabolism.  Following administration subjects demonstrated increased cerebral circulation to the gray matter and concurrent improvement in memory function following administration. It was also found to increase glucose utilization in the brain and raises its metabolic rate.  

L-Huperzine improves memory retention. In a double-blind, randomized, placebo-controlled study students administered huperzine-A for four weeks had a significantly higher memory quotient than the placebo group. Scores of Chinese language class were also elevated in the treatment group. L-Huperzine, improves cognitive function and counteracts cognitive decline. In a double-blind, randomized, controlled study of patients with Alzheimer’s disease (AD), subjects receiving huperzine-A supplementation demonstrated a significant increase in psychological evaluation scores compared to the control group. In a double-blind, placebo-controlled study of AD patients, administration of huperzine resulted in significantly improved memory, cognitive function, and behavioral function compared with placebo.